নেত্রকোণা মেডিকেল কলেজ, নেত্রকোণা

1. Introduction: Brief historical background  Basic concepts of immunity: Definition, classification, types and components with examples.

2. Immune system:  Organs, cells and soluble components

3. Antigens and Immunogens:  Terms and definitions: antigen, immunogen, hapten, epitope, paratope. Criteria of immunogenicity.

4. Major histocompatibility complex (MHC/ HLA):  Terms and definitions, types and distribution, clinical and biological significance.

5. Immunoglobulins and Antibodies:  Terms and definitions, classification, structure, biological properties and functions.  Monoclonal antibodies.

6. Complements:  Terms and definitions, activation, biological functions and clinical significance, deficiency disorders.

7. Mechanisms of immune response :  Antibody and cell mediated immune response.  Primary and secondary immune response

8. Hypersensitivity:  Terms and definitions, classifications, mechanisms, clinical significance with examples.  Atopy, desensitization.  Tests for Type-I reaction: Patch test, RAST, serum IgE assay.

9. Transplantation and Tumour immunity:  Terms and definitions, types and outline of prevention of graft rejection.  Tumour antigens, role in diagnosis and clinical significance.  Immunosurveillance

10. Tolerance and Autoimmunity:  Definition and classification of tolerance  Terms and definitions, basic concepts and mechanism of development of autoimmuniy.

11. Immunodeficiency disorders and immunotherapy:  Classification with examples

12. Agents of immunotherapy and biologics.

13. Immunodiagnostic tests  Terms and definitions, types and applications in diagnostic medicine  Agglutination, precipitation, ELISA, Western blot test, PCR and RT-PCR